Protein Details: Aquaporin PIP2-5

Protein ID

ICDB_Pro_1705

Protein Name

Aquaporin PIP2-5

Gene Name

PIP2-5

Organism

Zea mays (Maize)

Length

285 amino acids

AlphaFoldDB

AF-Q9XF58-F1-model_v4.pdb

Function

Water channel required to facilitate the transport of water across cell membrane. Its function is impaired by Hg(2+). May play a role in water uptake from the root surface. Active as homomers. Increased activity when heteromerization with PIP1-2.

Sequence

MAKDIEAAAAHEGKDYSDPPPAPLVDAEELTKWSLYRAVIAEFVATLLFLYITVATVIGYKHQTDAAASGPDAACGGVGVLGIAWAFGGMIFILVYCTAGVSGGHINPAVTFGLFLARKVSLVRALLYIVAQCLGAICGVGLVKGFQSAFYVRYGGGANELSAGYSKGTGLAAEIIGTFVLVYTVFSATDPKRNARDSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSLGAAVIYNNDKAWDDHWIFWVGPFIGAAIAAAYHQYVLRASAAKLGSSASFSR

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Specifically expressed in roots; in the exodermis; endodermis and xylem parenchyma; Polar localization to the external periclinal side of epidermal cells in root apices

DOI ID

10.1104/pp.125.3.1206; 10.1093/pcp/pcg168; 10.1104/pp.122.4.1025; 10.1105/tpc.017194; 10.1007/s11103-006-9022-1

RefSeq

NP_001105616.1